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Cannabigerol

Cannabigerol (CBG) is a non-psychoactive cannabinoid found in the Cannabis genus of plants. Cannabigerol is found in higher concentrations in hemp rather than in varieties of Cannabis cultivated for high tetrahydrocannabinol (THC) content and their corresponding psychoactive properties. By the time most strains of cannabis are cultivated, they will have trace amounts of CBG, somewhere below 1%.

Cannabigerol has been found to act as a high affinity α-adrenergic receptor agonist, moderate affinity 5-HT receptor antagonist, and low affinity CB receptor antagonist. It also binds to the CB receptor, but whether it acts as an agonist or antagonist at this site is unknown.