Crossword clues for bilirubin
The Collaborative International Dictionary
Bilirubin \Bil`i*ru"bin\, n. [L. bilis biel + ruber red.] (Physiol.) A reddish yellow pigment present in human bile, and in that from carnivorous and herbivorous animals; the normal biliary pigment.
Douglas Harper's Etymology Dictionary
Wiktionary
n. (context biochemistry English) A bile pigment that is product of the breakdown of the heme portion of hemoglobin (which occurs within macrophages as they digest red blood cells), extremely high levels of which cause jaundice.
WordNet
n. an orange-yellow pigment in the bile that forms as a product of hemoglobin; excess amounts in the blood produce the yellow appearance observed in jaundice [syn: hematoidin, haematoidin]
Wikipedia
Bilirubin (formerly referred to as haematoidin) is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the body's clearance of waste products that arise from the destruction of aged red blood cells. First the hemoglobin gets stripped of the heme molecule which thereafter passes through various processes of porphyrin catabolism, depending on the part of the body in which the breakdown occurs. For example, the molecules excreted in the urine differ from those in the feces. The production of biliverdin from heme is the first major step in the catabolic pathway, after which the enzyme biliverdin reductase performs the second step, producing bilirubin from biliverdin.
Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases. It is responsible for the yellow color of bruises and the yellow discoloration in jaundice. Its subsequent breakdown products, such as stercobilin, cause the brown color of feces. A different breakdown product, urobilin, is the main component of the straw-yellow color in urine.
It has also been found in plants.
Usage examples of "bilirubin".
Measurements of blood sugar, serum amylase, serum acetone, bilirubin, and blood urea nitrogen were normal.
At eleven, he was seen by the surgeons who agreed that gall-bladder infection was possible, even though bilirubin and amylase tests were normal.
She went into more details, knowing Monk shared a background in medicine: low platelet counts, rising bilirubin levels, edema, muscle tenderness with bouts of rigidity around the neck and shoulders, bone infarctions, hepatosplenomegaly, audible murmurs in the heartbeat, and strange calcification of distal extremities and vitreous humor of the eyes.
He smelled of bilirubin and yellow sweat and wore week-old eyeliner that simply did not fly if one needed a shave.
The amount of hydrochloric acid and bilirubin and glucose and glycogen and gloconol produced and absorbed and produced in my body.
O'Connor, and the dates those tests were first described in clinically practical terms: X ray: chest and abdomen (1905-15) White cell count (about 1895) Serum acetone (1928) Amylase (1948) Calcium (1931) Phosphorus (1925) SCOT (1955) LDH (1956) CPK (1961) John O'Connor 45 Aldolase (1949) Lipase (1934) CSF protein (1931) CSF sugar (1932) Blood sugar (1932) Bilirubin (1937) Serum albumin/globulin (1923-38) Electrolytes (1941-6) Electrocardiogram (about 1915) Prothrombin time (1940) Blood pH (1924-57) Blood gases (1957) Protein-bound iodine (1948) Alkaline phosphatase (1933) Watson-Schwartz (1941) Creatinine (1933) Uric acid (1933) If one were to graph these tests, and others commonly used, against the total time course of medical history, one would see a flat line for more than two thousand years, followed by a slight rise beginning about 1850, and then an ever-sharper rise to the present time.
The second problem echoed the bilirubin issue: the uroporphyrin enzyme deficiency prevented the breakdown of heme's toxic protein precursorsporphyrins.