ATSC is the Advanced Television Systems Committee standards.
ATSC may also refer to:
- Advanced Television Systems Committee, the committee that wrote the ATSC Standards
- Acetone thiosemicarbazone, a chemical compound
- Air Technical Service Command, one of the many predecessors of the Air Force Material Command
- Army Training Support Center, a United States Army facility at Fort Eustis
- ATSC (UK) Ltd, the manufacturer of the fake ADE 651 bomb detection device