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amniotic fluid embolism

n. (context pathology English) A complication of pregnancy characterized by movement of amniotic fluid past the placenta

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Amniotic fluid embolism

An amniotic fluid embolism (AFE) is a rare childbirth ( obstetric) emergency in which amniotic fluid, fetal cells, hair, or other debris enters the mother's blood stream via the placental bed of the uterus and triggers an allergic-like reaction. This reaction then results in cardiorespiratory (heart and lung) collapse and massive hemorrhaging ( coagulopathy). It was first formally characterized in 1941. While it is rare (between 1 in 8,000 and 1 in 80,000 deliveries), the high mortality makes it the fifth most common cause of maternal mortality in the world, in some estimates.