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Activella

Activella (also sold as Estracomb, Kliofem and Novofem) is a combination drug of estradiol and norethisterone acetate used for the treatment of vasomotor symptoms, vulvar and vaginal atrophy and osteoporosis associated with menopause.

Activella supplied as film-coated tablets containing 1 mg estradiol and 0.5 mg norethisterone acetate. Activella is marketed by Novo Nordisk.