Crossword clues for acromegaly
The Collaborative International Dictionary
Acromegaly \Ac`ro*meg"a*ly\, n. [NL. acromegalia, fr. Gr. 'a`kron point, peak + ?, ?, big.] (Med.) Chronic enlargement of the extremities and face.
Douglas Harper's Etymology Dictionary
"gigantism due to activity of pituitary after normal growth has ceased," 1886, from French acromégalie, from medical Latin acromegalia, from Greek akron "extremity" (see acrid) + megas "great" (fem. megale; see mickle). Said in contemporary literature to have been coined 1885 by French physician Dr. Pierre Marie.
Wiktionary
n. (context disease English) A chronic disease marked by enlargement of the bones of the extremities, face, and jaw that is caused by over-activity of the pituitary gland.
WordNet
n. enlargement of bones of hands and feet and face; often accompanied by headache and muscle pain and emotional disturbances; caused by overproduction of growth hormone by the anterior pituitary gland (due to a tumor) [syn: acromegalia]
Wikipedia
Acromegaly is a condition that results from excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlarged of the hands and feet. There may also be enlargement of the forehead, jaw, and nose. Other symptoms may include joint pain, thicker skin, deepening of the voice, headaches, and problems with vision. Complications of the disease may include type 2 diabetes, sleep apnea, and high blood pressure.
Acromegaly is typically due to the pituitary gland producing too much growth hormone. In more than 95% of people the excess production is due to a benign tumor, known as a pituitary adenoma. The condition is not inherited from a person's parents. Rarely acromegally is due to tumors in other parts of the body. Diagnosis is by measuring growth hormone after a person has drank glucose or measuring insulin-like growth factor I in the blood. After diagnosis medical imaging of the pituitary is carried out to look for an adenoma. If excess growth hormone is produced during childhood the result is gigantism.
Treatment option include surgery to remove the tumor, medications, and radiation therapy. Surgery is usually the prefered treatment and is most effective when the tumor is smaller. In those in whom surgery is not effective, medications of the somatostatin analogue or GH receptor antagonist type may be used. The effects of radiation therapy are more gradual than that of surgery or medication. Without treatment those affected live on average 10 years less; however, with treatment life expectancy is typically normal.
Acromegaly affects about 6 per 100,000 people. It is most commonly diagnosed in middle age. Males and females are affected equally frequently. The first medical description of the disorder occurred in 1772 by Nicolas Saucerotte. The term is from Greek akron meaning "extremity" and mega meaning "large".
Usage examples of "acromegaly".
Though usually in such cases the growth is of an unbalanced or localized sort, as in acromegaly, where the bones of the hands or jaw become abnormally enlarged.
The Beast is the current Crompton, Leland, last of his line, a mystery writer who lives as a recluse in New Hampshire and suffers from acromegaly which has disfigured his features.
For some reason, acromegaly seems to have a high incidence among Swedes.
In regard to the physical aspects, in extreme cases acromegaly can produce a giant.
But with the incidence of acromegaly, the extremities continue to become enlarged, the hands and feet, the bones and cutaneous tissues of the face.
The small handful of Wamphyri diseases were mainly hereditary: various animalisms, several forms of insanity, aggressive autisms, acromegaly and other bone disorders.
In a flat, quiet tone, Lakesh declared, "Advanced achondroplasia, with indications of acromegaly.
INDEX INDEX Abduc«ns nerve, 207 Accessory nerve, 208 Acetylcholine, 132 autonomic nervous system and, 218 Achromatism, 297 Acoustic area, 177 Acoustic nerve, 208, 265 Acromegaly, 95 ACTH, 82 autonomic nervous system and, 219 Addison, Thomas, 76 Addison's disease, 76 ADH, 63 Adrenal glands, 40 Adrenalin, 41 schizophrenia and, 335 Adrenergic nerves, 218 Adrenochrome, 335 Adrenocorticotrophic hormone, 82 Alanine, 10 Albinos, eyes of, 276, 277 Aldosterone, 80 Allergies, histamine and, 43-44 All-or-none law, 137 Alpha waves, 178 Amine group, 9 Amino acids, 8 abbreviations of, 11, 12 arrangements of, 14, 15, 36 Amino acids, contd.
It was Anselmo, he could tell from the corner of his eye—no mistaking that hand like a bleached ham, that face big as that of a white horse, for in addition to being a submoronic deaf-mute, the ancient Sicilian had acromegaly.